O presente artigo tem por finalidade avaliar o problema intuicionista com as provas não construtivas na matemática. Para esta posição construtivista o princípio do terceiro excluído, da lógica clássica, não deve operar sobre demonstrações matemáticas. As provas não construtivas não são aceitas, sendo as provas construtivas as únicas com caráter positivo. Após uma breve introdução ao intuicionismo e seu idealizador, o artigo abordará a relação entre o princípio do terceiro excluído e as provas na matemática, para assim falar sobre o (...) problema das provas não construtivas e da consequência em não aceitá-las. Ao tomar a matemática unicamente como um empreendimento de construção mental, o intuicionismo quebra com o realismo platônico dominante e estabelece um debate frutífero sobre os fundamentos da matemática. (shrink)

A evolução dos meios de comunicação propiciou um massivo fluxo informacional, trazendo consigo alguns entraves. O fenômeno das fake news é produto dessa mudança na sociedade, afetando de diversas formas a vida das pessoas e inclusive a possibilidade de uma escolha plena e livre de influências, sua liberdade de expressão, pensamento e informação. Nesse contexto, este evento se torna gravoso para o nosso Estado Democrático, na medida que influencia o comportamento, as escolhas políticas, a conduta social e a solidez da (...) própria democracia. Diante do exposto, o objetivo do presente trabalho é refletir como as fake news interferem no Estado Democrático de Direito no Brasil e o deformam. Trata-se de uma revisão bibliográfica, documental e qualitativa. Propõe-se, por meio desse estudo, explicitar o que é esse fenômeno tão complexo das fake news e compreender as diversas formas de como ele pode afetar nosso sistema democrático, baseando-se nas ideias discursivas de Habermas. (shrink)

For the epic journey of autumn migration, long-distance migratory birds use innate and learned information and follow strict schedules imposed by genetic and epigenetic mechanisms, the details of which remain largely unknown. In addition, bird migration requires integrated action of different multisensory systems for learning and memory, and the hippocampus appears to be the integration center for this task. In previous studies we found that contrasting long-distance migratory flights differentially affected the morphological complexity of two types of hippocampus astrocytes. Recently, (...) a significant association was found between the latitude of the reproductive site and the size of the ADCYAP1 allele in long distance migratory birds. We tested for correlations between astrocyte morphological complexity, migratory distances, and size of the ADCYAP1 allele in three long-distance migrant species of shorebird and one non-migrant. Significant differences among species were found in the number and morphological complexity of the astrocytes, as well as in the size of the microsatellites of the ADCYAP1 gene. We found significant associations between the size of the ADCYAP1 microsatellites, the migratory distances, and the degree of morphological complexity of the astrocytes. We suggest that associations between astrocyte number and morphological complexity, ADCYAP1 microsatellite size, and migratory behavior may be part of the adaptive response to the migratory process of shorebirds. (shrink)

Este trabajo investiga las interrelaciones entre la regulación y los as-pectos económicos y ambientales en una comunidad de agricultores familiares en la región conocida como Zona da Mata Mineira, en el estado brasileño de Minas Gerais. El estudio es producto de una acti-vidad de extensión realizada entre 2016 y 2018, y tuvo como objetivo asesorar a los pequeños productores en el proceso de adecuación legal de la producción. Durante este período se realizaron cerca de cinco reuniones entre investigadores y comuneros, (...) en las que se analizaron las dificultades encontradas por los pequeños productores en relación con el referido proceso. Las experiencias reportadas fueron confron-tadas con el régimen legal regulatorio para la actividad acuícola en Brasil, tomando como categorías de análisis los atributos de norma-tividad y facticidad del sistema legal. Se concluyó que la regulación ambiental en el área de la acuicultura en Brasil, diseñada para grandes productores, carga de manera desproporcionada a los pequeños pro-ductores, generando un desequilibrio económico injustificado. Como aporte a la teoría, se propone, en definitiva, la formulación de un con-cepto de regulación jurídica inclusiva, cuyos rasgos distintivos inclu-yen la participación social y la promoción de la alfabetización jurídica como derecho fundamental. (shrink)

DISSERTAÇÃO DE MESTRADO MELO, Mário Henrique Resende. O significado histórico religioso da venerável ordem terceira de Nossa Senhora do Monte do Carmo de Sabará nas minas oitocentistas: práticas religiosas e representações. 2011. 100 folhas. Dissertação (Mestrado) – Pontifícia Universidade Católica de Minas Gerais, Programa de Pós-graduação em Ciências da Religião, Belo Horizonte.

RESUMO A série Black Mirror, transmitida entre 2011 e 2023 pela Netflix, tornou-se um fenômeno de mídia e seus episódios mostraram formas de interação homem-máquina (terminologia também referida como humano-computador). O nome da série se refere ao fato de que, quando uma tela é desligada, ela se torna um espelho negro que reflete a imagem do usuário. Este artigo1 tem como objetivo analisar os efeitos da interação homem-máquina nas organizações produtivas apresentadas em Black Mirror. Esta pesquisa utilizou a análise do (...) discurso, principalmente a partir das contribuições de Mikhail Bakhtin. O método consistiu em três etapas que contaram com a colaboração de estudantes de graduação e pós-graduação em Engenharia de Produção, integrando ensino e pesquisa e desenvolvendo o senso crítico dos pesquisadores-iniciantes. Os resultados indicam que, nas organizações apresentadas na série Black Mirror, há uma transição do conceito de fatores humanos para fatores ciborgues, bem como o uso da interação homem-máquina para promover o controle social. (shrink)

Although shared decision-making is a standard in medical care, unilateral decisions through process-based conflict resolution policies have been defended in certain cases. In patients who do not stand to receive proportional clinical benefits, the harms involved in interventions such as cardiopulmonary resuscitation seem to run contrary to the principle of non-maleficence, and provision of such interventions may cause clinicians significant moral distress. However, because the application of these policies involves taking choices out of the domain of shared decision-making, they face (...) important ethical and legal problems, including a recent challenge to their constitutionality. In light of these concerns, we suggest a re-conceptualization of informed non-dissent as an alternative approach in cases where the application of process-based policies is being considered. This clinician-directed communication model still preserves what is valuable in such policies and salvages professional integrity, while minimising ethical and legal challenges. (shrink)

Este estudo visa a apresentar e analisar a Carta XXXVIII, de 1º de outubro de 1666, escrita por Espinosa. De conteúdo exclusivamente matemático, seu texto responde a uma questão de probabilidade aplicada a jogos de apostas em que é preciso preservar, para todos os jogadores, a mesma chance de ganhar. Para isso, apresentaremos o contexto histórico e exporemos detalhadamente o uso e o sentido da terminologia empregada por Espinosa ao longo de suas explicações. Subsidiariamente, em apêndice, fornecemos, de maneira espelhada, (...) o original holandês da carta e nossa tradução para o português. (shrink)

Este trabajo analiza el famoso y “terrible” diálogo que presenta Tucídides en su Guerra del Peloponeso entre los atenienses y los melios y busca destacar elementos que mostrarían una visión trágica de la historia y de los asuntos humanos por parte de su autor. Para ello se utiliza, como elemento heurístico, la interpretación que Nietzsche hizo de este diálogo, específicamente en los parágrafos 92 y 93 de Humano, demasiado humano I. De acuerdo con la interpretación del texto se sugiere que (...) la de Nietzsche es, al menos, incompleta, para afirmar lo cual se usa un esquema de análisis con dos planos: el de lo particular-visible y el de lo general-invisible. La dialéctica entre estos planos, que se expande en el diálogo mismo entre lo que concretamente éste dice y lo que deja en silencio, revelaría en qué medida el análisis de Nietzsche se centra solo en uno de ellos, mientras que el otro, como complemento del primero, revelaría la visión más amplia del propio autor del diálogo como una visión trágica. (shrink)

La forma sonata es una de las estructuras musicales más empleadas desde el siglo XVIII, tanto en obras para instrumento solista como en música de cámara, sinfónica e incluso en ópera. La disposición formal de este tipo de construcciones se basa en las relaciones establecidas entre las sensaciones sonoras de reposo, inestabi-lidad y tensión, generadas inicialmente en el discurso armónico. Sin embargo, estas relaciones se pueden situar también en los niveles melódico, rítmico y tímbrico. En este documento se presenta el (...) primer movi-miento del Cuarteto No 1 Op. 18 en Fa Mayor de Ludwig van Beethoven, compuesto en forma de sonata, como estructura basada en relaciones rítmicas. El principal fundamento teórico de este estudio se halla en la Teoría de Estratos de Nicolai Hartmann. (shrink)

Este artigo tem por objetivo criticar a teoria do modelo ocidental de guerra, proposta por Hanson, a partir do que a historiografia tem identificado como seus principais problemas: a alegada continuidade da arte da guerra ocidental através dos séculos, começando com os gregos antigos; e o chamado “contraste asiático”, com alguns dos seus desdobramentos. Assim, o texto está dividido em três seções: 1) a apresentação e os méritos da teoria de Hanson; 2) suas bases clássicas, ou a ênfase da arte (...) da guerra grega na batalha decisiva como uma “escolha cultural”; 3) as críticas pertinentes. (shrink)

A partir de uma pesquisa bibliográfica de caráter qualitativo, este artigo busca identificar o potencial do relato de reformular a teoria moral da dignidade humana, tornando a normatividade dela decorrente sensível às peculiaridades das minorias sociais. Este trabalho, dentre várias outras produções, tem como referencial teórico principal a obra Torture and Dignity: An Essay on Moral Injury (2015), de Jay Bernstein, além de utilizar, para fins de compreensão do caráter intergeracional do relato, o livro O que os cegos estão sonhando? (...) (2012), organizada por Noemi Jaffe. Estabelecido tal panorama, busca-se discutir a hipótese de que o relato possui funções subjetivas, morais e sociais que, juntas, são capazes de fazer com que o indivíduo retome o controle de seu corpo após experiências de degradação, senso de corporeidade esse que, ao tornar igualmente relevantes os aspectos voluntário e involuntário do ser, tornam contextuais as concepções de dignidade humana e de Direitos Humanos. (shrink)

The modern concept of ‘style’ – from which ‘stylistics’ is derived, a discipline that witnessed the quarrel between Linguistics and Literary studies in the 20th century – has inherited from Ancient Rhetoric its substance and was largely used as a direct translation from the Latin concept ‘_elocutio_’ and also as a translation for Greek concepts, such as ἑρμηνεία, λέξις and φράσις. There are still some other concepts that seem intimately connected to ‘style’, for instance ‘_ornatum_’ and ‘_decorum_’. Considering that classical (...) references of ‘style’ present themselves essential to write the history of this modern concept, this paper seeks to present a catalog of ancient concepts that have found in ‘style’ their traditional translation, as well as attempting to build a short history of each of these translation paths. (shrink)

In this paper, we aim to bring to discussion the concept of locus amoenus, a common denomination of locus communis (topos, for the greeks), that makes reference to the ideal landscape according to the norms of the ancient idyllic poetry. We will describe and analyze the locus amoenus from an 18th century Italian poetry perspective, more specifically from the fables of Luigi Fiacchi, a poet and Catholic priest of that century. The analysis will focus on the references, either direct or (...) not, that the author, known by the epithet ‘Il Casio’, does to the Classical Antiquity. (shrink)

Os Grundrisse são a primeira expressão da crítica ontológica da economia política feita por Marx. Ao tratar, das formas sociais que precedem a sociedade capitalista, Marx já se afastara da centralidade, até então atribuída, à forma jurídica da propriedade na explicação da dinâmica social de toda a historicidade do ser social. Aqui, Marx já vislumbra que na sociedade do capital há uma essência (valor) que é permanência na mudança e que se modifica na quantidade e não na qualidade e que, (...) ao mesmo tempo, é a forma específica da riqueza, forma de dominação social específica da sociedade capitalista, forma social automediadora e médium social. Essa substância só existe socialmente no interior de um inexorável processo de autoexpansão que é nomeado por Marx como capital. Capital, desse modo, revela-se um constrangimento lógico que em seu nível mais crucial independe da forma jurídica da propriedade para se efetivar no mundo humano. (shrink)

The lack of public support for climate change policies and refusals to vaccinate children are just two alarming illustrations of the impacts of dissent about scientific claims. Dissent can lead to confusion, false beliefs, and widespread public doubt about highly justified scientific evidence. Even more dangerously, it has begun to corrode the very authority of scientific consensus and knowledge. Deployed aggressively and to political ends, some dissent can intimidate scientists, stymie research, and lead both the public and policymakers to oppose (...) important public policies firmly rooted in science. -/- To criticize dissent is, however, a fraught exercise. Skepticism and fearless debate are key to the scientific process, making it both vital and incredibly difficult to characterize and identify dissent that is problematic in its approach and consequences. Indeed, as de Melo-Martín and Intemann show, the criteria commonly proposed as means of identifying inappropriate dissent are flawed and the strategies generally recommended to tackle such dissent are not only ineffective but could even make the situation worse. -/- The Fight Against Doubt proposes that progress on this front can best be achieved by enhancing the trustworthiness of the scientific community and by being more realistic about the limits of science when it comes to policymaking. It shows that a richer understanding of the context in which science operates is needed to disarm problematic dissent and those who deploy it. This, the authors argue, is the best way forward, rather than diagnosing the many instances of wrong-headed dissent. (shrink)

Reprogenetic technologies, which combine the power of reproductive techniques with the tools of genetic science and technology, promise prospective parents a remarkable degree of control to pick and choose the likely characteristics of their offspring. Not only can they select embryos with or without particular genetically-related diseases and disabilities but also choose embryos with non-disease related traits such as sex. -/- Prominent authors such as Agar, Buchanan, DeGrazia, Green, Harris, Robertson, Savulescu, and Silver have flocked to the banner of reprogenetics. (...) For them, increased reproductive choice and reduced suffering through the elimination of genetic disease and disability are just the first step. They advocate use of these technologies to create beings who enjoy longer and healthier lives, possess greater intellectual capacities, and are capable of more refined emotional experiences. Indeed, Harris and Savulescu in particular take reprogenetic technologies to be so valuable to human beings that they have insisted that their use is not only morally permissible but morally required. -/- Rethinking Reprogenetics challenges this mainstream view with a contextualised, gender-attentive philosophical perspective. De Melo-Martín demonstrates that you do not have to be a Luddite, social conservative, or religious zealot to resist the siren song of reprogenetics. Pointing out the flawed nature of the arguments put forward by the technologies' proponents, Rethinking Reprogenetics reveals the problematic nature of the assumptions underpinning current evaluations of these technologies and offers a framework for a more critical and skeptical assessment. (shrink)

The argument from inductive risk has been embraced by many as a successful account of the role of values in science that challenges the value-free ideal. We argue that it is not obvious that the argument from inductive risk actually undermines the value-free ideal. This is because the inductive risk argument endorses an assumption held by proponents of the value-free ideal: that contextual values never play an appropriate role in determining evidence. We show that challenging the value-free ideal ultimately requires (...) rejecting this assumption. (shrink)

The use of genome embryo editing tools in reproduction is often touted as a way to ensure the birth of healthy and genetically related children. Many would agree that this is a worthy goal. The purpose of this paper is to argue that, if we are concerned with justice, accepting such goal as morally appropriate commits one to rejecting the development of embryo editing for reproductive purposes. This is so because safer and more effective means exist that can allow many (...) more prospective parents to achieve the same valued goal and that offer additional benefits. (shrink)

Philosophers of science, particularly those working on science and values, often talk about the need for science to be socially responsible. However, what this means is not clear. In this paper, we review the contributions of philosophers of science to the debate over socially responsible science and explore the dimensions that a fruitful account of socially responsible science should address. Our review shows that offering a comprehensive account is difficult. We contend that broad calls for socially responsible science that fail (...) to attend to relevant dimensions are not the solution, as they preclude meaningful changes to research institutions and practices. We conclude that narrower, more explicit accounts are more likely to lead to substantive transformation. (shrink)

The therapeutic misconception has been seen as presenting an ethical problem because failure to distinguish the aims of research participation from those receiving ordinary treatment may seriously undermine the informed consent of research subjects. Hence, most theoretical and empirical work on the problems of the therapeutic misconception has been directed to evaluate whether, and to what degree, this confusion invalidates the consent of subjects. We argue here that this focus on the understanding component of informed consent, while important, might be (...) too narrow to capture the ethical complexity of the therapeutic misconception. We show that concerns about misplaced trust and exploitation of such trust are also relevant, and ought to be taken into account, when considering why the therapeutic misconception matters ethically. (shrink)

Although science is our most reliable producer of knowledge, it can also be used to create ignorance, unjustified doubt, and misinformation. In doing so, agnotological practices result not only in epistemic harms but also in social ones. A way to prevent or minimise such harms is to impede these ignorance-producing practices. In this paper, I explore various challenges to such a proposal. I first argue that reliably identifying agnotological practices in a way that permits the prevention of relevant harms is (...) more difficult than it might appear. I focus on an identifying criterion that many find apt for the task: bad faith motives. I then consider an objection—that reliable criteria are unnecessary to successfully address the concerns raised by agnotological strategies—and I show that it fails. I conclude by exploring other ways of conceptualising the problems attributed to agnotological practices. In particular, I challenge the focus on misinformation as the main problem of concern. (shrink)

Recently, some have proposed moral bioenhancement as a solution to the serious moral evils that humans face. Seemingly disillusioned with traditional methods of moral education, proponents of bioenhancement believe that we should pursue and apply biotechnological means to morally enhance human beings. Such proposal has generated a lively debate about the permissibility of moral bioenhancement. We argue here that such debate is specious. The claim that moral bioenhancement is a solution - whether permissible or not - to the serious moral (...) problems that affect human beings is based on several problematic framing assumptions. We evaluate here three of such assumptions: the first rests on a contested understanding of morality, the second consist in a mistaken conception of human moral problems, and the third relates to problematic presuppositions grounding the interpretation of existent scientific evidence presented to defend moral bioenhancement. Once these framing assumptions are identified and critically evaluated, it becomes clear that the moral bioenhancement debate is misguided. (shrink)

A growing number of jurisdictions hold that gamete donors must be identifiable to the children born with their eggs or sperm, on grounds that being able to know about one's genetic origins is a fundamental moral right. But the argument for that belief has not yet been adequately made.

A new reprogenetic technology, mitochondrial replacement, is making its appearance and, unsurprisingly given its promise to wash off our earthly stains --or at least the scourges of sexual reproduction--, John Harris finds only reasons to celebrate this new scientific feat.1 In fact, he finds mitochondrial replacement techniques (MRTs) so “unreservedly welcome” that he believes those who reject them suffer from “a large degree of desperation and not a little callousness.”2 Believing myself to be neither desperate nor callous, but finding myself (...) also no closer at all – not even after reading his article—to following Harris in welcoming these technologies wholeheartedly, it seems appropriate to respond. (shrink)

Proponents of moral enhancement believe that we should pursue and apply biotechnological means to morally enhance human beings, as failing to do so is likely to lead to humanity's demise. Unsurprisingly, these proposals have generated a substantial amount of debate about the moral permissibility of using such interventions. Here I put aside concerns about the permissibility of moral enhancement and focus on the conceptual and evidentiary grounds for the moral enhancement project. I argue that such grounds are quite precarious.

Because of the important benefits that biomedical research offers to humans, some have argued that people have a general moral obligation to participate in research. Although the defense of such a putative moral duty has raised controversy, few scholars, on either side of the debate, have attended to the social context in which research takes place and where such an obligation will be discharged. By reflecting on the social context in which a presumed duty to participate in research will obtain, (...) this article shows that decontextualized discussions of this putative moral obligation are problematic. (shrink)

The disclosure policies of scientific journals now require that investigators provide information about financial interests relevant to their research. The main goals of these policies are to prevent bias from occurring, to help identify bias when it occurs, and to avoid the appearance of bias. We argue here that such policies do little to help achieve these goals, and we suggest more effective alternatives.

Science is our most reliable producer of knowledge. Nonetheless, a significant amount of evidence shows that pluralities of members of publics question a variety of accepted scientific claims as well as policies and recommendation informed by the scientific evidence. Scientific misinformation is considered to play a central role in this state of affairs. In this paper, I challenge the emphasis on misinformation as a primary culprit on two grounds. First, the phenomenon of misinformation is far less clear than what much (...) discussion about the topic would lead one to believe. The evidence regarding the amount of misinformation that exits as well as its role in people’s harmful behaviors is at best conflicting and at worst completely useless. Second, the prominence given to misinformation and its harms on people’s behaviors disregards the role of values in policymaking and treats scientific information as if it were the only information necessary to make policy decisions. At a minimum, these problems call for caution regarding the emphasis on this phenomenon. After all, if the problem is incorrectly diagnosed, the solutions that are being offered to address the problem of misinformation are bound to at best inadequate and at worst dangerous. (shrink)

Many have argued that allowing and encouraging public avenues for dissent and critical evaluation of scientific research is a necessary condition for promoting the objectivity of scientific communities and advancing scientific knowledge . The history of science reveals many cases where an existing scientific consensus was later shown to be wrong . Dissent plays a crucial role in uncovering potential problems and limitations of consensus views. Thus, many have argued that scientific communities ought to increase opportunities for dissenting views to (...) be heard and taken seriously. Such opportunities are necessary for both limiting the influence .. (shrink)

ABSTRACT The purpose of this paper is to examine critically Julian Savulescu's claim that people should select, of the possible children they could have, the one who is expected to have the best life, or at least as good a life as the others, based on the relevant, available genetic information, including information about non‐disease genes. I argue here that in defending this moral obligation, Savulescu has neglected several important issues such as access to selection technologies, disproportionate burdens on women, (...) difficulties in determining what is best, problems with aggregate effects of individual choices, and questions about social justice. Taking these matters into account would call such a moral requirement into serious question. (shrink)

Hastings Center Report, Volume 52, Issue 5, Page 3-3, September–October 2022.

Recent advances in biotechnologies have led to speculations about enhancing human beings. Many of the moral arguments presented to defend human enhancement technologies have been limited to discussions of their risks and benefits. The author argues that in so far as ethical arguments focus primarily on risks and benefits of human enhancement technologies, these arguments will be insufficient to provide a robust defence of these technologies. This is so because the belief that an assessment of risks and benefits is a (...) sufficient ethical evaluation of these technologies incorrectly presupposes that risk assessments do not involve value judgements. Second, it presupposes a reductionist conception of ethics as merely a risk management instrument. Each of these assumptions separates ethical evaluation from discussion and appraisal of ends and means and thus leaves important—indeed, essential—ethical considerations out of view. Once these problematic assumptions are rejected, it becomes clear that an adequate defence of human enhancement technologies requires more than a simple balance of their risks and benefits. (shrink)

According to sparse modalism, the notion of essence can be analysed in terms of necessity and naturalness. In this paper, I develop and defend a version of sparse modalism that is equipped with a non-standard, relativized conception of naturalness. According to this conception, properties and relations can be natural to different degrees relative to different kinds of things, and relations can be natural to different degrees relative to different slots. I argue that this relativized version of sparse modalism can accommodate (...) various cases that the standard, non-relativized version can’t. The alternative version can accommodate cases where a relation is essential to a relatum but merely necessary to another, cases where a property is essential to an object but merely necessary to another, and cases where a less-than-perfectly natural property is essential to an object. (shrink)

Philosophers of science have come to accept that contextual values can play unavoidable and desirable roles in science. This has raised concerns about the need to distinguish legitimate and illegitimate value influences in scientific inquiry. I discuss here four such concerns: epistemic distortion, value imposition, undermining of public trust in science, and the use of objectionable values. I contend that preserving epistemic integrity and avoiding value imposition provide good reasons to attempt to distinguish between legitimate and illegitimate influences of values (...) in science. However, the trust and the objectionable values concerns constitute no good reason for demarcation criteria. (shrink)

Varro's De lingua Latina is a treasure trove of information. Of the originally twenty-five books, six have come down to us more or less complete. Among these, Books 5–7 give us many hundreds of etymologies, and Books 8–10 discuss the question whether Latin morphology is regular or not. What Varro rarely comments on is sociolinguistic variation. The sociolinguistic comments in Varro's work can almost be counted on one hand. For instance, in 5.162 Varro remarks that cenaculum, from cena ‘dinner’, means (...) ‘attic’ in Roman Latin, but that the original meaning was, as one might expect, ‘dining-room’, a meaning preserved in the non-Roman dialects of Latium, Falerii and Corduba in Spain; the meaning also lives on in religious uses in Lanuvium. In 7.96, Varro tells us that some words are pronounced with -ae- by some, but with -ē- by others. We know that non-Roman varieties of Latin monophthongized -ae- earlier than the Roman dialect did. Varro mentions pairs like scaena / scēna ‘stage’, a loan from Greek σκηνή, which shows that -ae- is hypercorrect here. Interestingly, only in one such pair is the variant with -ē- ascribed to country people, in the name Maesius / Mēsius, and this is indeed the only pair where the diphthong -ae- is original rather than the result of hypercorrection. (shrink)

Informed consent is recognized as a primary ethical requirement to conduct research involving humans. In the investigations with the use of human biological material, informed consent (IC) assumes a differentiated condition on account of the many future possibilities. This work presents suitable alternatives for IC regarding the storage and use of human biological material in research, according to new Brazilian regulations. Both norms – Resolution 441/11 of the National Health Council, approved on 12 May 2011, and Ordinance 2.201 (NATIONAL GUIDELINES (...) FOR BIOREPOSITORIES AND BIOBANKS OF HUMAN BIOLOGICAL MATERIAL FOR RESEARCH PURPOSE) of the Brazil Ministry of Health, approved on 14 September 2011 – state that the consent of subjects for the collection, storage and use of samples stored in Biobanks is necessarily established by means of a Free and Informed Consent Form (ICF). In order to obtain individual and formal statements, this form should contain the following two mutually exclusive options: an explanation about the use of the stored material in each research study, and the need for new consent or the waiver thereof when the material is used for a new study. On the other hand, ICF suitable for Biorepositories must be exclusive and related to specific research. Although Brazilian and international regulations identify the main aspects to be included in the IC, efforts are still necessary to improve the consent process, so that the document will become a bond of trust between subject and researcher. (shrink)

Several feminist philosophers of science have argued that social and political values are compatible with, and may even enhance, scientific objectivity. A variety of normative recommendations have emerged regarding how to identify, manage, and critically evaluate social values in science. In particular, several feminist theorists have argued that scientific communities ought to: 1) include researchers with diverse experiences, interests, and values, with equal opportunity and authority to scrutinize research; 2) investigate or "study up" scientific phenomena from the perspectives, interests, and (...) conditions of marginalized stakeholders potentially affected by the research; and 3) make gender, ethnicity, class, and geographical location "visible," or use them as categories of analysis when appropriate. Yet, more work is needed to determine what exactly these recommendations would require, and the benefits they would yield, in specific research contexts. Using the recent development of the human papillomavirus (HPV) vaccines, we examine how these three feminist recommendations would have applied. We argue that these principles would have yielded several epistemic and social benefits in the HPV case, as well as in biomedical research more generally. That is, biomedical research guided by these principles would not only be epistemically superior, but also more socially responsible. (shrink)

Although surprising to some proponents of sex selection for non-medical reasons (Dahl 2005), a considerable amount of critical debate has been raised by this practice (Blyth, Frith, and Crawshaw 2008; Dawson and Trounson 1996; Dickens 2002; Harris 2005; Heyd 2003; Holm 2004; Macklin 2010; Malpani 2002; McDougall 2005; Purdy 2007; Seavilleklein and Sherwin 2007; Steinbock 2002; Strange and Chadwick 2010; Wilkinson 2008). While abortion or infanticide has long been used as means of sex selection, a new technology—preimplantation genetic diagnosis (PGD)—has (...) become a highly efficient, and arguably less controversial, way of ensuring the birth of a child of a particular sex. PGD, used in combination with in vitro .. (shrink)

The U.S. Food and Drug Administration (FDA) announced recently that food products derived from some animal clones and their offspring are safe for human consumption. In response to criticism that it had failed to engage with ethical, social, and economic concerns raised by livestock cloning, the FDA argued that addressing normative issues prior to issuing a final ruling on animal cloning is not part of its mission. In this article, the authors reject the FDA's claim that its mission to protect (...) and advance public health can be accomplished without considering ethical issues or without making value judgments. The authors offer two arguments in support of their position. First, the agency's mission statement presupposes significant normative commitments and judgments. Second, the FDA's risk assessment of food products from cloned animals and their offspring is itself clearly shaped by a variety of normative commitments. (shrink)

It is argued here that bioethicists might inadvertently be promoting genetic determinism: the idea that genes alone determine human traits and behaviours. Discussions about genetic testing are used to exemplify how they might be doing so. Quite often bioethicists use clinical cases to support particular moral obligations or rights as if these cases were representative of the kind of information we can acquire about human diseases through genetic testing, when they are not. On other occasions, the clinical cases are presented (...) in simplistic ways that portray genetic testing as yielding information more accurate than it actually is. It is concluded that, because of the problematic implications that the ideology of genetic determinism might have for individuals’ wellbeing and for our public policies, bioethicists should be careful to present these issues in ways that do not promote questionable ideas about the causal role of genes in human diseases and behaviours. (shrink)